Amicus Therapeutics Biotech Company

Amicus Therapeutics, a global biotechnology company was founded in 2002 in Cranbury, NJ. Its primary focus is to develop therapies for genetic, rare and orphan diseases. They are unique in that as of 2014, Amicus Therapeutics had the widest grouping of small molecule pharmacological chaperones among their competitors in the industry. Amicus has developed therapies for some rare diseases, such as Lysosomal Storage Disorders Fabry disease (affecting 1 in 117,000 people) and Pompe disease (affecting 5,000 to 10,000 people worldwide) and the genetic connective skin disorder Epidermolysis Bullosa (affecting 20 in 1,000,000 infants). In fact, Amicus Therapies has established a productive pipeline that is continuously generating a steady flow of new and effective therapies to treat genetic disorders. Visit Yahoo Finance to learn more about Amicus Therapeutics.

Their most promising product is Migalastat, a medicine that treats Fabry disease. It is currently in late-stage development. Another product in late-stage development that would also be a first-to-market therapy is SD-101, a product that treats Epidermolysis Bullosa (EB). Amicus is using all their advanced techniques to create an enzyme replacement therapy for Fabry and Pompe disease. In addition, they hope to use similar therapies to treat other Lysosomal Storage Disorders (LSDs). Their program ATB200/AT2221 is a uniquely biologically engineered therapy to treat Pompe disease. It is to be used with a pharmacological chaperone.

The clinical trials that Amicus Therapeutics is currently conducting include one for treating the genetic mutations in the CDKL5 gene causing the CDKL5 protein deficiency. The CDKL5 protein deficiency causes a disorder that manifests clinically as persistent seizures and severe impairment in neurological development, all occurring in infancy. As a consequence these children cannot walk, or perform basic self maintenance and they may also have scoliosis, visual impairments, sensory issues, and gastrointestinal complications.


Amicus Therapeutics acquired Callidus Biopharma, a competitor in 2013 and Scioderm, Incorporated, a rare disease company in 2015. Both acquisitions have put Amicus in a better position to release their first therapy. Amicus Therapeutics has its finger on the release of some very important therapies for several rare diseases. Their successful development and release will finally make the lives hundreds of children and adults more livable. View the market summary of Amicus Therapeutics at

Bold Choices are Important in Business

People have changed their shopping habits, and they prefer online shopping because how easy it is. Clothing industry took to online shopping like fish to water, but sportswear was slow to follow. The online shopping was there, but women could not buy sportswear the fit and would look good. However, the modern consumers know what they want, and the lack of option was what caught the interest of Don Ressler and Adam Goldenberg since they follow market trends.

Techstyle Fashion Group was started because Don Ressler and Adam Goldenberg saw an opportunity where nobody else did at the time. It was a time when women didn’t have a lot of choice with activewear because it was either too expensive or lacked quality. More affordable active clothing was in no shape to look good, and there were issues in sizing. It seemed that companies didn’t realize that women come in all shapes and sizes. Don Ressler and Adam Goldenberg saw the opportunity to create something better and something new to fill the empty spot in the market.

They were not well-versed in fashion by any means, but they had something else. They were driven and dedicated to work hard for success. Both worked together before venturing out on their own, so learning about fashion was a great challenge. It allowed both men to dig deeper and find out what the trends were and how to achieve it.

Customers nowadays appreciate and choose companies that have a clear message to their customer base. People look for values they believe in, and if a company shares these values, people find them more trustworthy. Open communication with clients is also an important aspect, and it was always important for both Don Ressler and Adam Goldenberg. They are not showing any signs of slowing down.

They are not afraid to make bold business choices and use innovation in business. Modern technology is one of the most important parts of any business that is ready and willing to develop and continue to evolve. Companies that don’t change lose customers rather than gain new ones. Don Ressler and Adam Goldenberg know how important it is to their clients to be able to shop online and find the kind of clothes that look good and are made to last.

These days companies don’t just sell products and services. They sell an entire experience in a bundle so people look for it and businesses like Techstyle Fashion Group work on it.

OSI Group: The Present & The Future of Global Food Solutions

OSI Group, formally known as Otto & Sons, is the worldwide leader in custom food solutions, and it is revolutionizing the game for the better. This Aurora-based company has been around since its inception in 1909. The company was founded by German immigrant Otto Kolshowski, and he produced some of the freshest beef products in the area. The company was actually operated by the family, but as it began to grow, more employees were added to the staff. OSI Group also supplied McDonald’s during its earlier days even after cryogenic food processing came into existence. West Chicago is the location of its first high-volume meat plant, but as of today, it has plants in numerous locations around the globe. In a sense, this is truly a rags to riches type of story.

OSI Group is at the apex of the industry because it does so many progressive things. It would be hard trying to find another food supplier that can distribute, process, develop and manage to such high degree. Types of foods? OSI produces just about everything that’s eatable like:

• Flatbread
• Panini
• Pot Roast
• Cookies
• Fresh Dough
• Beef Patties
• Meat Balls
• Cucumber
• Tomatoes
• Pizza
• Link Sausages
• And many others

The options are nearly endless and this company works closely with all of its clients throughout the process. With such fine global flavor knowledge and culinary skill, OSI produces some of the best concept-to-table solutions. There is a lot of hard work that goes on behind the scene, but nobody makes it look easier than this company. So, what is the future of the company? OSI Group is looking to be around for many more decades and possibly for many more centuries. Its client list is very impressive as it serves Subway, Starbucks, Pizza Hut, KFC and Papa John’s Pizza. For those who are interested in working as a team member of OSI Industries or for those who have the entrepreneurial spirit, OSI Group is looking for people like you to come and join this diverse team.

OSI Group Info:

Fashion for People of All Sizes From Don Ressler

Women have the right to look however they want and enjoy all of the different styles. There is one catch. They have to be small in order to enjoy it. This is one major issue in the fashion industry. Many of the fashion labels have a size limit in the clothes they offer. To make things worse, the sizing has shrunk according to some women. Therefore, women have two layers of a problem in the fashion industry. Fortunately, there are efforts to change this for women. Don Ressler, himself has made plenty of progress in the fashion industry by making Fabletics an all-inclusive venture.

One of the common issues that larger women have to deal with is the fact that they have to look very hard for clothing. Then when they find clothes that are in their size, they often have to settle for some of the bland items. Just because women are larger does not mean that they don’t want anything unique. Kate Hudson and Don Ressler as entrepreneurs have realized that there is such a major gap in the fashion industry for active wear and larger women. This is when they have seized the opportunity to provide for these groups.

With Fabletics, they have decided to think about ways that they can bring forth the same designs to larger women so that they can enjoy the clothes offered to them. Also, a lot of clothing stores seem to leave out the vast majority of women with their exclusivity to the smaller woman. Fabletics capitalizes on this major opportunity for not only offering larger women better fitting outfits, but also clothes that actually feel good to the touch because of the fabric used to create these clothes.

When women try on clothes from Fabletics and other brands that Don Ressler has set up, one of the first things that they are going to notice is that there is a lot of comfort that comes with wearing these items. This is also a pleasurable feeling that helps improve the moods of people when they wear these items. This could also keep them coming back for more fashion items.

Why You Should Include Organo Gold’s Premium Coffee in Your Shopping Basket Next Time You Shop

In case you have been wondering whether drinking coffee has any benefits health-wise, wonder no more. The Annals of Internal Medicine recently published two studies in support of coffee drinking. The studies suggested that habitual coffee drinking does not only lead to better health but possibly more extended life. Although the studies could not directly pinpoint reasons as to why a slew of health benefits are inherent in the beverage, scientists strongly attributed habitual coffee drinking to a decrease in cases of heart diseases, cancer, stroke, and urological diseases such as prostate cancer. Also, researchers who participated in the studies including America’s Veronica W. Setiawan confirmed that their findings were the same whether their subjects were African-American, Japanese Americans, Latinos, or whites. Follow Organo Gold on Instagram.

The two studies which are gaining popularity with coffee lovers across the globe were done in America and Europe. Although different researchers did them, the methodologies adopted by the studies were more or less similar. Both studies investigated a group of coffee and non-coffee users. The American one examined slightly less than 200 thousand Americans, and the European investigation covered over half a million people in ten countries. Needless to say, the two studies were concluded on a similar note: coffee-lovers live up to 18 percent longer than non-drinkers.

The news did not excite only coffee drinker’s worldwide but also coffee marketing companies such as Organo Gold. The global network marketing company has carved a niche as a premium coffee distributor. The company has a presence not only in the U.S but also other countries.


Bernardo T. Chua established Organo Gold 2008. He envisioned a world-class company distributing healthy bioactive coffee products enhanced with Ganoderma lucidum for maximum potency. Chua is determined to assist people to attain their health goals. The company sells body management and personal care products to boot. Organo Gold is available on eBay.

A Success Story With White Shark Media

Not all businesses have specialties in online marketing. For this reason, White Shark Media steps in to help businesses. Under the leadership of Alexander Nygart, the firm is doing an exceptional job. It has helped businesses to exploit the opportunities for online marketing. Since the company began, it has achieved this objective and left clients with a fulfilled experience.

Today, traditional marketing methods are not delivering results satisfactorily. They need to be reinforced with digital marketing. Additionally, online presence is potential for acquiring customers. Every business should utilize this opening. Whether big or small, White Shark does not discriminate. All clients are important, and they are handled according to their needs.

Among the services offered are in PPC, SEM, and SEO. These are instruments for driving traffic towards a client’s website. A part of this traffic is expected to convert into real customers. At an affordable price, White Shark assists the customers to maximize their benefits and have a good reap.

White Shark Media began as a small agency, and it is now a renowned firm in online marketing. White Shark manages every client separately. Since there is no one solution-fit –all, the firm customizes strategies for each client. This company is loyal and supportive when clients have concerns or inquiries. After implementing a solid marketing campaign, they it and ensure it is producing results as promised. White Shark is always committed to the success of its clients.

The Commendable Contributions of Dr. Mark Holterman in Healthcare

Currently, Dr. Mark Holterman is a successful individual who doubles as a professor of surgery and pediatrics. He provides these services at the University of Illinois, College of Medicine. One of the core qualifications that makes him suitable to work in the renowned university is his degree in medicine and immunology which he acquired from the University of Virginia. Therefore, his education background is indisputable.

Dr. Mark Holterman receives so much praise as a surgeon from his patients due to the impeccable skills he possesses. In addition, his good works have been identified by other bodies that have awarded him severally. For instance, he was awarded for being among the list of America’s top doctors. In fact, he has been awarded for this very reason on seven different occasions since 2008. He also won the Patient’s Choice Award in 2012, 2014 and 2015. In addition to education and experience that he has in the healthcare industry, he stands out for being a good listener whereby he listens to children’s concerns and responds to their questions. View Mark Holterman’s Linkedin profile.

One of the best methods for a professional to sharpen his or her skills is by joining organizations that enhance teamwork and development. Dr. Mark Holterman has joined several professional organizations. Most importantly, he is a dedicated member of the American Diabetes Association (ADA) that was founded in 1940. This professional organization focusses on researches and education. Also, it deals with activities that are related to treatment, prevention, and cure of diabetes which is quite common. Since ADA is a non-profit organization, it uses its funds to sponsor various programs and missions. Read more at to know more about Dr. Mark Holterman.

Other than ADA, Dr. Mark Holterman is also a member of The Hannah Sunshine Foundation. In fact, he is one of the founding members. This organization primarily focuses on the use of cellular and regenerative therapies specifically for children who are found to have rare diseases. The formation of this foundation was inspired by three people including Sarah Hughes who was suffering from systemic juvenile idiopathic arthritis (SJIA). This is a serious condition that affects various parts of the body including the joints, the cardiovascular as well as the respiratory system.


Desiree Perez Is There To See The Deal Between Live Nation And Jay Z Coming To A Close

The ten-year, $150 million deal in 2008 between Jay Z and Live Nation is ending. This may result in a buy-sell situation since either party could buy the company, or sell their stake. According to sources, Jay Z plans to leave the recorded side of music. An insider confirmed the deal is not being extended, and Live Nation no longer buys recorded music. The artists in Roc Nation include Shakira, Meek Mill, Fat Joe, Jay Z, and Rihanna.

Desiree Perez is Jay Z’s top executive at Roc Nation. Her meeting with the CEO and Chairman of the Universal Music Group, Lucian Grainge, led to speculation about UMG purchasing a stake in the company. This would enable Jay Z to develop additional artists. Insiders at UMG say there is already a distribution deal between the company and Roc Nation. If they agreed to a larger investment, UMG would have a bigger stake in the artists at Roc Nation.

According to an insider at UMG, the partnership already holds enough significance. Despite this, it was stated furthering business with Jay Z would be great. The end of the deal with Roc Nation has not yet been discussed at UMG. The reps for Universal, Live Nation, Roc Nation, and Jay Z all failed to comment.

Desiree Perez has served ROC Nation as the Chief Operating Officer since 2009. As one of the members of the team, she is involved in numerous areas including publishing, management, and labeling operations. She negotiated Rihanna’s deal with Samsung, and is considered an extremely tough negotiator. As a woman in a field mainly dominated by men, Desiree Perez has still managed to become successful. She is one of Jay Z’s closest associates, and has been for nearly twenty years. Her track record regarding running SC Enterprises is incredibly long. and Follow him

Attorney Ricardo Tosto’s Career

Brazil takes pride of having many lawyers this has been made possible due to a significant number of law schools that are well established in the country. Brazil is recognized as a country of lawyers, in 2010, it was ranked the third country with the highest number of lawyers in the globe. The United States took the second position, having more than 1 million professional lawyers. The first place was India that had a slightly high number of lawyers than the U.S.

The reason behind Brazilians’ huge number of lawyers is not just loved for law and that everybody has the passion for becoming a lawyer, but due to the availability of many law schools in the country. It’s estimated that Brazil has more law institutions than that of all the world’s nations put together.

There exist 1,240 graduation courses dealing with law in Brazil contrary to the total amount of the world law schools which click 1,100. This data was released by National Council of Justice (CNJ) in the year 2010. Brazil got more than 8000 lawyers who are registered by the bar association-the lawyers officially allowed by law to stand in for clients in a court of law. Also over three million qualified lawyers from different law schools who are yet to be approved. Those lawyers who have already graduated from the bar have the upper hand to begin teaching law or venture into any relevant law field.

Ricardo Tosto de Oliveira Carvalho is the developer of one of the biggest law companies regarding the representation and human resource base in Brazil. The firm has more than 500 employees.

Ricardo Tost has superior experience in law with almost 2o years of practice. He is the pioneer of the mass litigation model that is mostly harnessed in Brazil. As a successful business lawyer in the country, he is hired by prominent entities and corporates to represent them in their cases. Ricardo’s firm managed to appropriately deal with the way of organizing mass litigation which increased the goodwill to the company from various clients the firm represents. Ricardo Tosto has an indisputable reputation of handling matters of Ricardo lacrosse camp.


Technological Solutions for Crime at Securus Technologies

Securus Technologies is a competitive firm that offers technological solutions to civil and criminal justice. At Securus we offer a diversity of services, a case in point is monitoring services, public safety, corrections, and investigation. Our primary goal is to mitigate crimes that precede within and outside all incarceration environments.


Our main goal at Securus is to make sure that the rights of the innocent are fully protected against any form of violation. To meet this noble goal, we develop at least one law enforcement and correction product every week.


At Securus, we use feedback from our clients as a benchmark to come up with more advanced and personalized innovations. One satisfied client sent us an email which commended our contraband system. Through this service, they were able to trace a corrupt staff member in their firm. Securus enabled them to get all the phone call information and a search warrant for the perpetrator.


Securus offers monitoring services for incarceration environments. The calls monitored have enabled our clients to track inmate alcohol use and civilian drug trafficking in correction facilities. Our technology has also been resourceful to various incarceration facilities. One of our clients was particularly happy with the level of commitment exhibited at Securus to bring about efficiency in correctional facilities.


According to the letters and emails we receive, our customers are widely attracted to our vision and emerging capabilities in making sure justice is fair to all. For instance, an agency wrote to us about a decline of contraband incidences in their facility. Our collaborative team enabled them to instill proactive measures in deterring communication malpractices in their facility. LBS has also helped several clients in enforcing the law especially in cash transfers, drug, and illegal asset acquisitions.


Securus has its headquarters in Dallas, Texas. We offer several services including biometric analysis, incident management, investigation, inmate self-service, monitoring, and information management. We serve over of 3, 450 law enforcement facilities, public safety, and correctional agencies. We also serve more than 1.2 million inmates.